Immune Deficiencies
Immune deficiencies may be due to genetic or acquired defects, and these defects lead to increased risks to certain infectious diseas…
Posts
Maternal Immunologic Agents Transferred to the Recipient Infant
The mother transmits immune factors to the offspring both through the placenta and milk. Large quantities of IgG are transmitted via …
Ontogeny of Immunity
There is an orderly development of the immune system during the intrauterine period. Pluripotent stem cells appear first in the yolk …
Diseases Due to Immune Responses to Infectious Agents
Five major types of immune responses to infecting agents may lead to disease. 1) Circulating immune complexes formed from microbial a…
Defense against Infections
Cutaneous and Mucosal Defense The first line of defense against most potential pathogens is the skin and mucous m…
The Complement System
The Complement System The complement system consists of a group of glycoproteins in the extracellular space that can be stimulated in…
Recognition of Self and Immune Tolerance
Self Tolerance The immune system has evolved to distinguish between self and non-self antigens and to largely el…