This cell is different from the other polynuclear cells because of the affinity of its granules for the acid stains like eosin. To be able to distinguish this cell, it is absolutely necessary to stain. In a comparative study, by Nolan and Kelleher, the former has shown that the Hansel stain was superior to the Wright stain for eosinophiluria. The presence of urinary eosinophils is a useful indicator of acute allergic interstitial nephritis. Eosinophiluria is also seen in conditions other than nephritis.
Causes of eosinophiluria
| Acute allergic interstitial nephritis |
| Rapidly progressive glomerulonephritis |
| Acute glomerulonephritis |
| IgA nephropathy, Henoch-Schönlein purpura |
| Prostatitis |
| Schistosomiasis |
| Chronic pyelonephritis |
| Graft rejection (acute phase) |